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However, their activity is reported to decrease with age, which is one of the risk factors for cataracts
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Nowadays, FOXO4-DRI studies are focused on the following aspects: osteoarthritis (senescent chondrocyte clearance), metabolic dysfunction (insulin resistance and obesity-associated senescence), neurodegeneration (eliminating senescent brain cells), and fibrotic diseases (idiopathic pulmonary and liver fibrosis)
elegans had not been examined previously, the catabolite regulator CRP and the cysteine biosynthesis gene CysE
Immunofluorescence staining was conducted to assess antioxidant capacity via SOD expression and to evaluate macrophage polarization using CD86 (M1 marker) and CD206 (M2 marker)
