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2024 Mar 30;13(4):425
In rats with Parkinsonian-like symptoms, NMDA administration produces a smaller response from VTA dopamine neurons than in control rats
the clinical relevance of this finding in humans is unknown, and in UK and EU prescribing information this is noted as a precaution rather than a formal contraindication but individuals with a personal or family history of medullary thyroid carcinoma or multiple endocrine neoplasia type 2 (MEN2) should discuss this with their doctor
Chronic oxidative stress in the brainstem and peripheral nerves keeps the autonomic nervous system locked in a state of sympathetic dominance (the "fight-or-flight" response)
M.1999Na+/H+ exchange inhibition induces intracellular acidosis and differentially impairs cell growth and viability of human and rat hepatocarcinoma cells
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