fda safety communication semaglutide naion 2025 January Part 1: warning for RSV vaccines; Depo Provera contraceptive link to brain tumors; iron infusion therapy risk; Ozempic and rare eye condition; Gemtesa for overactive bladder; more Semaglutide linked to increased risk

Red-flag symptoms requiring immediate medical attention include severe abdominal pain, persistent vomiting, jaundice, dark urine, clay-colored stools, or signs of hypoglycemia

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A sudden, severe headache that reaches maximum intensity within seconds to minutesoften described as a "thunderclap headache"requires immediate emergency evaluation, as this pattern can indicate serious conditions such as intracranial hemorrhage, though such events are not specifically linked to semaglutide

[3] Hashemzaei, M., Fanoudi, S., Rezaei, H., Musavi, S

Cureus, 15(10)

These effects could potentially shield the brain from the damaging effect of the disorder, leading to better long-term outcomes for patients