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Storage instructions for vitamin B12

Gastrointestinal disturbances with B12 supplements typically relate to excipients such as sorbitol, mannitol, or lactose rather than the vitamin itself

Often, once injections start, patients discontinue separate oral B supplements, sticking to perhaps just a basic multivitamin or prenatal vitamin at most

The FDA has not reviewed or approved compounded products for any use for safety, efficacy, or quality

The people who are at the highest risk of B12 insufficiency or deficiency are older adults, those with atrophic gastritis, gastrointestinal disorders, pernicious anemia, those who have had gastrointestinal surgery, vegans, and vegetarians

BNF recommends hydroxocobalamin rather than cyanocobalamin for vitamin B12 deficiency