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GLP-1 drugs could fill the gap in addiction treatment So far, multiple systemic reviews have been conducted to provide a comprehensive analysis of clinical trials to determine the impact of GLP-1 receptor agonists in reducing substance use disorder in patients

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Lu Z et al

Greater weight reduction may also require more careful monitoring, especially for gastrointestinal side effects, hydration, nutrition adequacy, gallbladder symptoms, medication interactions, and muscle preservation

A depletion in NAD + results in bioenergetic failure of mitochondria and eventually cell death 90,91

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