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Detected effects regarding the kinetic parameters of K26A and D90A were highly similar to the ScGrx7 mutants K105A and E170A, respectively (Supplementary Figs 1116

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Glutathione is an antioxidant that is present in small amounts in most people, but some free radicals cause damage to it, resulting in cellular decay and eventually aging

However, it is worth noting that the extent of the increase and the duration for which these elevated levels are maintained could vary between the two

The homogenates were centrifuged at 4 C for 20 min at 12,000 g , and the resulting supernatants were used for MDA analysis