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The second is gastrointestinal inflammation: BPC-157s gastric origin gives it exceptional affinity for gut tissue, and the preclinical data on gut permeability, mucosal repair, and intestinal motility is the strongest body of evidence for this compound
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DOI: 10.1016/0092-8674(93)90415-M IGF-1 Axis and Anabolic Signalling Landmark studies establishing the GH/IGF-1 axis including the somatomedin hypothesis refinements by LeRoith, Laron, and colleagues defined IGF-1 as the primary mediator of GHs anabolic and growth-promoting effects, confirmed the liver as the primary source of circulating IGF-1, and established the research framework for GH deficiency and GH replacement biology that underpins current pre-clinical GH axis research
Liang KL, Yu SJ, Huang WC, Yen HR
While BPC 157 peptide is remarkably stable for a peptide, sublingual administration may offer even more efficient delivery for systemic effects
