The choice between Vitamin B12 supplements vs injections depends on several factors, including: Your needs: If you have a severe B12 deficiency or require rapid B12 replenishment, B12 shots may be the more effective option
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The vitamin is injected directly into muscle (intramuscular) or under the skin (subcutaneous) and is released gradually into the bloodstream
Animal foods particularly high in vitamin B12 include bluefin tuna, Pacific oysters, salmon, Atlantic herring, mackerel, sardines, trout, and tuna
Lautrup S, et al
Proton pump inhibitors and similar medications that lower stomach acid might decrease the absorption of vitamin B12 from food, but this is less of a concern when receiving B12 injections because they bypass the digestive system entirely