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Originally, severe gastrointestinal issues were considered rare
The Bottom Line Microdosing semaglutide means using weekly doses of 0.05 to 0.25 mg to achieve partial appetite suppression with fewer side effects and lower cost than standard treatment
You should contact your GP if you experience: New or worsening sexual dysfunction , such as reduced libido, erectile difficulties, or problems with arousal or orgasm Unexpected changes in sexual desire that concern you or affect your relationships Symptoms that may indicate hormonal imbalances , such as irregular menstrual periods, breast tenderness, or mood changes Psychological concerns including depression, anxiety, or body image issues that impact your intimate life Seek urgent medical attention if you experience: Severe, persistent abdominal pain (with or without vomiting) Signs of gallbladder disease (pain in upper right abdomen, fever, yellowing of skin/eyes) Sustained vomiting or diarrhoea leading to dehydration Severe or recurrent hypoglycaemia Your doctor can conduct a thorough assessment, which may include reviewing your medication regimen, checking hormone levels, assessing cardiovascular health, and evaluating psychological factors
Lee Y, Shin JM, Jang S, Choi DK, Seo MS, Kim HR, et al
Recent phase 2 clinical trial data evaluating the activity and safety of Retatrutide in subjects with type 2 diabetes demonstrate its pronounced effects on both glycemic control and body weight reduction
Unless you have exceptional circumstances (modest weight loss goal, strong lifestyle capacity, history of successful maintenance), assume Retatrutide will be ongoing treatment
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