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Individuals with a personal or family history of medullary thyroid carcinoma or MEN2 are typically excluded from trials due to precautionary class-effect concerns

Laurent G, de Boer VCJ, Finley LWS, Sweeney M, Lu H, Schug TT, Cen Y, Jeong SM, Li X, Sauve AA et al (2023) SIRT4 represses peroxisome proliferator-activated receptor activity to suppress hepatic fat oxidation

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