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In 3T3-L1 adipocyte cell models, 5-Amino-1MQ at 30 M concentration produced significant reductions in intracellular 1-MNA levels, confirming target engagement
PMID: 33557137
The prevention of the glucagon rise might improve the beneficial effects of the combination therapy to enhance glucose control and may support this combination therapy in clinical practice [81]
Engelhardt K, Ferguson M, Rosselli JL
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