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Dosing Strategies: Start Low, Go Slow Sublingual semaglutide should follow a titration approach, with typical starting doses of 0.5 mg to 1 mg daily for new patients

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3 Results 3.1 Study search and selection A total of 12,717 records were retrieved, including 531 from PubMed, 3,386 from Embase, 84 from the Cochrane Library, 483 from Web of Science, and 8,233 from Scopus, the details of the search strategy was shown in Supplementary Table S1

Glucagon-receptor activation contributes effects on hepatic lipid metabolism and whole-body energy expenditure that are absent from GLP-1 mono-agonists and dual GLP-1/GIP agonists