glp 1 hypoglycemia Localized GLP1 receptor pre-internalization directs pancreatic alpha cell to beta cell communication GLP-1 receptor signalling promotes β-cell

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Preclinical in vitro and in vivo studies indicate that GLP-1RA treatment does not exacerbate cancer risk in patients with type 2 diabetes and concurrent pancreatic cancer [13]

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Methods Animal studies All animal studies were performed according to protocols approved by the University Committee on Animal Resources at the University of Rochester Medical Center