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Inflammation-associated oral mucosal melanin hyperpigmentation Under circumstances that are not well defined, certain inflammatory cytokines and mediators have the capacity to promote the production of -MSH by oral melanocytes and keratinocytes and to upregulate the expression of MC1R of melanocytes resulting in increased biosynthesis of melanin
The Maillard reaction is the most common pathway known to form AGEs
Understanding the typical duration of side effects, factors that influence them, and effective management strategies can help patients navigate treatment successfully and know when medical attention is needed
