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Lu et al., 2024)

The benzyl alcohol preservative prevents bacterial contamination that could degrade the peptide or introduce confounding variables in research assays

For these reasons, professional oversight is necessary to navigate the lack of standardized human dosing and to ensure the purity of the source

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The 2025 EMJ Dermatology scoping review reached the same conclusion: low-molecular-weight HA penetrates the dermis while high-molecular-weight HA delivers surface hydration and barrier protection