tirzepatide and depo provera (MOUNJARO® / ZEPBOUND®) BIRTH CONTROL PILLS Important Information About Pregnancy Prevention If you are taking tirzepatide (Mounjaro® or Zepbound®) and use birth control pills, there is an important medication interaction What You Need to Know

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Whether continuous stimulation of the HPG axis over years produces receptor downregulation or other adaptive changes that reduce efficacy over time is a question that longitudinal observational data is beginning to answer, but no definitive answer exists yet

Non-English studies were excluded

Patients who master proper injection technique experience fewer local side effects, maintain better medication consistency, and achieve more predictable clinical outcomes compared to those with inconsistent injection practices

Limitations of use: - It has not been studied in patients with a history of pancreatitis