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Transplantable rat glucagonomas cause acute onset of severe anorexia and adipsia despite highly elevated NPY mRNA levels in the hypothalamic arcuate nucleus
Together, these actions are thought to produce more pronounced weight loss and metabolic improvements than dual or single receptor agonists
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Postgrad Med J 96(1133):156161 Singh K, Aulakh SK, Nijjar GS, Singh S, Sandhu APS, Luthra S, et al (2024) Rebalancing the gut: glucagon-like peptide-1 agonists as a strategy for obesity and metabolic health
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