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Aging Cell 20 , e13443 (2021)
Due to how GLP-1 medications slow the emptying of your stomach, patients can experience gastrointestinal side effects
TB-500 is a synthetic fragment (Ac-LKKTETQ) of the 43-amino-acid protein thymosin beta-4, studied for actin-driven cell migration and tissue repair
This creates an unfortunate situation where effective treatment exists but isn't available to everyone who needs it, highlighting the urgent need for continued advocacy
In the connection to inflammation, we showed that elevation of pro-inflammatory cytokine IL-6, increased anxiety at the lightdark test, and smaller hippocampal volume characterized at baseline (before any applied stress) those mice that become susceptible after social defeat stress (SDS) with social withdrawal and impaired transcriptomic-wide changes in ventral dentate gyrus, and that administration of LAC promoted behavioral resilience at the SDS paradigm in this susceptible phenotype [27]