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General anesthesia affecting on developing brain: evidence from animal to clinical research

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BE / BA studies are conducted on 20, 40 or more of healthy human volunteers ( numbers may vary as per the Drug / Drug Authorities needs) , the objective being to assess the bioequivalence of Generic Medicine with the Branded Medicine

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Mechanistically, neuronal death protection from autophagy seems to involve the MET downstream mTOR signaling, whose activation (phosphorylation) is enhanced after tMCAO (Shang et al., 2010)

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Conceicao-Furber E, et al

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Testosterone propionate offers more frequent dosing requirements but provides tighter hormone control and less water retention

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How is purity verified?+ Each batch is tested to 99% by analytical HPLC, with identity confirmed by mass spectrometry

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