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It is not yet fully understood whether sulfate and other metabolic products of sulfur assimilation (O-acetylserine, cysteine, glutathione) act as signals in the regulation of sulfate uptake and transport, or in the expression of the sulfate transporters involved

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C., Salvador-Pascual, A., Arango, B

Concurrently, modulating the gut microbiome through specific probiotic supplements (e.g., Lactobacillus and Bifidobacterium strains with high myrosinase activity) represents a promising strategy to standardize and enhance the conversion of glucoraphanin to bioactive SFN, particularly when dietary SFN is obtained from cooked vegetables where plant myrosinase is inactivated (100, 101)