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The peptide's documented interaction with dopamine D2 receptors, including attenuation of amphetamine-induced hyperlocomotion and modification of haloperidol-induced catalepsy, suggests it could modulate the effects of dopamine agonists (pramipexole, ropinirole) or antagonists (antipsychotics) 4

doi: 10.3390/ijms20184559 Summary Keywords thiamine, riboflavin, niacin, pyridoxine, folate, cobalamin, complex B vitamins, neuropsychiatric manifestations Citation Han A, Almeida L, Anand N, Salloum IM, Kanaan S, Gadad BS and Daher JPL (2025) Exploring neuropsychiatric manifestations of vitamin B complex deficiencies

By inhibiting COX enzymes, ibuprofen may disrupt the balance of pro- and anti-inflammatory mediators, potentially leading to increased oxidative stress

One important trend is the focus on how astrocytic metabolism is dynamically regulated in response to neuronal activity

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