Understanding how GLP-1 works in the brain has become increasingly relevant as GLP-1 receptor agonist medicationslicensed in the UK for type 2 diabetes and weight managementproduce neurological effects including appetite suppression and potential neuroprotective benefits
10.1002/jcp.30958 8 Cortese-KrottM
Cai J, Chen Y, Seth S, Furukawa S, Compans RW, Jones DP
1 Introduction The advent of incretin-based therapies, including glucagon-like peptide-1 receptor agonists (GLP-1RAs) and their combinations, as pharmacological treatments for obesity and type 2 diabetes, has sparked intense debate about their role relative to traditional lifestyle interventions such as exercise and dietary modification
Flow cytometry data were acquired with a FACSCanto II (BD Biosciences, Madrid, Spain) and data analysis was performed using Cytomics FC500 with the CXP program
GIP adds metabolic improvements through pancreatic and fat tissue effects