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Neutron crystallographic evidence of lipase-colipase complex activation by a micelle
Znaidi S, Barker KS, Weber S, Alarco AM, Liu TT, Boucher G, et al
Hart EC, Joyner MJ, Wallin BG, Johnson CP, Curry TB, Eisenach JH
Comorbid conditions included obesity (BMI = 30.3 kg/m 2 ), hypertension managed with enalapril (20 mg/day) and lercanidipine (10 mg/day), hyperlipidemia on atorvastatin (40 mg/day) and depression treated with escitalopram (10 mg/day)
Older Age The risk of liver injury may increase with age
Biopsy-proven NASH : Patients with histologically confirmed NASH, particularly those with significant inflammation or early fibrosis (F1-F2), may be considered for off-label GLP-1 therapy, especially if they have failed lifestyle modification or have contraindications to other therapies like vitamin E or pioglitazone
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