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Acute toxicity studies in animals, if extrapolated to humans, implicate a single dose of 10-15 grams necessary to produce significant liver toxicity, although several human case reports have shown toxicity at doses less than 4 grams per day (likely due to having one or more risk factors for sensitivity to toxicity) (Amar 2007)
The demand for detailed analysis of the pathogenesis and clinical course of chronic diseases and viral diseases like COVID-19, as well as the use of efficacious therapies with minimal or no side effects are paramount
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Inflamm Res 2010, 59: 983988
It also plays a pivotal role in recycling other antioxidants like Vitamin C and E
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