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Less food means fewer calories for energy production, which might result in feeling colder, especially if the reduction in caloric intake is significant
Ultimately, the decision between tirzepatide and semaglutide should be made as part of a broader weight management strategy, taking into account lifestyle modifications, potential risks, and long-term sustainability
Interlinking between obesity and insulin resistance in PCOS Insulin resistance (IR) is a health issue described by a diminished ability of external or internal insulin to effectively promote the intake and utilization of glucose in comparison to a regular group [49]
In the second trial, SURPASS-2, tirzepatide administered at doses of 5 mg, 10 mg, or 15 mg showed superior efficacy compared to semaglutide (1 mg) in reducing body weight and HbA1c levels over 40 weeks in patients with T2DM inadequately controlled with metformin [66]
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