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Red de Investigacin en Atencin Primaria de Adicciones (RIAPAd), Instituto de Salud Carlos III (RD21/0009/0006)

Zmitek K, Amitek J, Hristov H, Butina MR, Kersmanc P, Pogacnik T

While tirzepatide itself does not suppress immunity, gastrointestinal side effectssuch as nausea, vomiting, and diarrhoeaare common, particularly during dose escalation

The advantage of the KGD sequence is that it does not block the adhesive functions of other RGD-dependent integrins, and therefore specifically inhibits platelet-dependent thrombus formation

Relatively infrequent cardiovascular events also limited the precision of some safety estimates

It helps to keep in mind that 'glutathione' exists in two forms in the cell: glutathione disulfide (GSSG) and glutathione (GSH)