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It is downregulated in gastric and colorectal cancers but upregulated in lung adenocarcinoma and breast tumors compared to normal tissue ( In gastric and colorectal cancer, high CHAC2 expression leads to reduced glutathione, elevated intracellular Ca 2+ and increased ROS, resulting in inhibited tumor growth, proliferation and migration

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What makes it selective: unlike GHRP-6 and GHRP-2, it stimulates GH release without significantly elevating cortisol, prolactin, or appetite

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This newly proposed, cost-effective optical detection method, which allows for varying the number and arrangement of LDRs, is applicable not only to eLODs but also to non-centrifugal LOC systems across various applications