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BMJ 2024;387:e080340.ArticlePubMedPMC 24
Ipamorelin was specifically engineered for GHS-R1a selectivity
Mounjaro has tirzepatide, a drug that acts on two hormones (GLP-1 + GIP) and may have a stronger effect on weight and metabolism
Unlike semaglutide, which is a modified peptide requiring special absorption-enhancing formulations, orforglipron is a small-molecule, non-peptide compound, meaning it's more stable, easier to manufacture, and potentially more affordable
Alternatively, if the acidosis fails to respond to N-acetylcysteine, this indicates the need to search further for alternative diagnoses
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