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doi: 10.1210/jendso/bvad056 191 GralskaJRanyUPolusADziewoskaAGrucaAZdzienickaAet al

This is useful because it shows that Wegovys longer-term appetite effect cannot be explained simply as food permanently sitting in the stomach

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Individual results vary based on adherence, dietary changes, physical activity, and baseline metabolic factors

Quick Answer: GLP-1 affects multiple brain regions including the hypothalamus, brainstem, mesolimbic reward system, hippocampus, and cortical areas involved in appetite regulation, reward processing, and cognitive function