The FDA has approved several non-stimulant medications for ADHD: Atomoxetine (Strattera): Increases norepinephrine in the brain Guanfacine (Intuniv): Affects certain areas of the prefrontal cortex Clonidine (Kapvay): Similar to guanfacine, it affects brain areas involved in attention and impulse control Non-stimulants generally have milder side effects compared to stimulants but may include fatigue, dry mouth, or nausea
Some peptides have FDA approval for specific medical conditions
(2025) New Molecules and Indications for GLP-1 Medicines Kompaniyets, Lyudmyla, et al
Semaglutide set the threshold at -15% in 2021, tirzepatide raised it to -21% in 2022, and retatrutide pushed it to -29% by the end of 2025
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