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Common side effects include nausea, vomiting, diarrhea, and constipation, which generally diminish over time

Reconstitution must be performed by trained personnel in an appropriate environment (e.g., a laminar flow cabinet or isolator where required by the protocol)

Over the past several years, researchers have examined large patient populations using real-world evidence, clinical trial follow-ups, and pharmacovigilance databases

The study also revealed that 24-hour urinary output decreased by 943 mL in patients taking dulaglutide

Indeed, only 2 months later (September 2023), Intuitive was already fielding worst case scenarios conference questions: People are sitting there worried, well, bariatric is going to slow, I don't know how much because of GLP-1s

Consequently, HILIC method development and validation require thorough risk assessment during method development to identify and minimize sources of variability and ensure robust methods suitable for GMP settings (which is entirely possible!)