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Pyridoxine (B) in high doses is known to interact with certain drugs: it can reduce the therapeutic efficacy of levodopa by increasing peripheral conversion of levodopa to dopamine (vitamin B speeds up decarboxylation)

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9: Vasireddi N, Hahamyan H, Salata MJ, Karns M, Calcei JG, Voos JE, Apostolakos JM

The onset of this resistance correlated with the activation of defense genes including a 20-fold increase in the transcript abundance of a GST gene ( GstA1 ) in wheat leaves infected with B

18, 254259.10.1094/MPMI-18-0254 10 FrendoP.JimnezM