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59 SMOKING AS A RISK FACTOR FOR CATARACT Smoking and tobacco chewing appear to induce oxidative stress and have been associated with both diminished levels of antioxidants, ascorbate, and carotenoids 60 , 61 , 62 , 63 , 64 , 65 and with enhanced cataract at a younger age
Like the binding mode for GSH, CP17 is bound within the VP1VP3 interprotomer pocket of the wt PV2 VLP through two critical arginine residuesArg243 and Arg258from neighbouring VP1 subunits, which form hydrogen bonds and salt-bridges with the carboxylate group of CP17 (Fig
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