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By comparison, the STEP 1 trial for semaglutide reported 14.9% at 68 weeks, and SURMOUNT-1 for tirzepatide reported 20.9% at 72 weeks
2017 Apr 4;7:127-140
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GLP-1RAs can also enhance glycolytic and oxidative pathways via AMPK activation, thereby limiting ectopic lipid accumulation and lipotoxic stress [55, 56]
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