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The search for new endpoints is necessary, given the complexity of skin irritation mechanism
We have a term for this when the bodys immune response goes into overdrive, cytokine storm, which is an uncontrolled inflammatory response from the immune system that overwhelms our bodys ability to compensate, and it contributes to why some people can rapidly die from certain infections or illnesses
Dysautonomia is a dynamic disease that can wax and wane, and diagnostic tests on a patients good day may not have positive findings despite the patients history of symptom flares
Cancer Lett 2002;183:18
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