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Suzuki T, Chret J, Scala FD, et al

Whether that translates into additive weight loss in humans is the open empirical question

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That distinction matters if you are dealing with fatigue, insulin resistance, stubborn weight gain, joint pain, elevated CRP, fatty liver, or the low-grade inflammatory state that often travels with metabolic dysfunction

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This drugs-vs-diet dichotomy was driven home to me last month when I met two physicians who ran a large medical group in the midwest