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One of the most promising areas of glutathione research is the role that it plays in cancer

Pathway enrichment analysis of these differentially prevalent metabolites revealed significant perturbations in metabolic networks including branched-chain aminoacids degradation, glutathione metabolism, threonine and 2-oxobutanoate degradation, gluconeogenesis, pyruvate metabolism, and glycine and serine metabolism (Figure S5)

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A conformational change may occur upon binding, potentially activating intracellular signaling pathways primarily involving G-proteins