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Animal models of depression show a decrease in cell proliferation (creation of new brain cells) as well as an increase in cell death (apoptosis).[ref] A relative lack of ATP due to mitochondrial dysfunction could also impact the ability of neurotransmitters to bind to their receptors

Interestingly, all patients with severe COVID-19 disease and high mortality risk have low basal GSH levels (Khanfar and Al Qaroot, 2020) that could explain an ominous outcome

Some of the best dietary sources of B12 include [3]: Beef Turkey Salmon, tuna, and clams Eggs Milk, yogurt, and cheese Nutritional yeast Fortified breakfast cereals Bananas and strawberries Spinach Kidney beans Due to dietary restrictions, vegetarians and vegans are at risk of low levels of B12

Vpr directly induces DNA damage, leading to the formation of both double-strand breaks and single-strand breaks 100,102

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2022;51(D1):D40917