A recent systemic review and meta-analysis published in the British Medical Journal (BMJ) found that while people tend to lose more weight more quickly with GLP-1s compared to traditional behavioral weight loss programs like exercise and diets, they may gain weight back faster after they stop taking the drugs compared to after they stop these lifestyle changes
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Liver Detoxification Pathways: How Methylation, Glutathione and Bile Remove Toxins The liver transforms medications, alcohol, hormones, environmental chemicals, microbial products and metabolic waste so they can be eliminated through urine or bile
Biol Chem 394:435448 Nagai K, Misonou Y, Fujisaki Y et al (2019) Topical application of l-carnosine to skeletal muscle excites the sympathetic nerve innervating the contralateral skeletal muscle in rats
If timing is your main question, When to Take Liposomal Glutathione for Best Results is a helpful next read
This is the part of pharmacy I respect most understanding that medicines dont just act they interact with physiology