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Endurance & Training Output More efficient mitochondria mean greater ATP output for extended performance

Some pills require strict fasting rules, while others offer more flexibility but may be less effective

For complete details on possible side effects and safety information, refer to the official prescribing information for Contrave and the safety info for Zepbound

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Abbreviations ASCVD: Atherosclerotic cardiovascular disease BMI: Body mass index CI: Confidence interval CKD: Chronic kidney disease CVD: Cardiovascular disease eGFR: Estimated glomerular filtration ratio GLP-1RA: Glucagon-like peptide-1 receptor agonist HFpEF: Heart failure with preserved ejection fraction HFrEF: Heart failure with reduced ejection fraction HHF: Heart failure hospitalization HR: Hazard ratio LDL: Low-density lipoprotein LVEF: Left ventricular ejection fraction MACE: Major cardiovascular events MRA: Mineralocorticoid receptor antagonist SGLT2: Sodium-glucose cotransporter 2 References Wong ND, Sattar N

An additional study demonstrated that acute IOP increase causes supportive glial cells to become proinflammatory and neurotoxic