lilly glp-1 drug Lilly's Trulicity joins pay-for-performance trend with Harvard Pilgrim deal Watch Lilly's GLP-1 Pill Outperforms

Expansion of GLP-1 drugs It did not take long for other companies to also jump on the GLP-1 bandwagon for the treatment of diabetes

Aging and Disease, 12 (8), 1948

Statistical methods All statistical methods were performed using JMP Pro 16 statistical software (JMP Statistical Discovery, LLC)

BENEFITS/ CLINICAL TRIALS Cagrilintide has demonstrated effective results in both monotherapy, as well as, more prominently, in combination with the GLP-1 receptor agonist, Semaglutide (referred to as CagriSema)

Differences in dosing schedules, potency, receptor affinity, and pharmacokinetic profiles help explain these variations in clinical outcomes

NNMT is an enzyme that grabs nicotinamide and methylates it, turning it into a waste product called 1-MNA that gets cleared from the body