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Studies have found that (Val 8 )GLP-1 protects synapses from the detrimental effects of A fragments on synaptic plasticity formation (171173)

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There are currently two approaches to harnessing the effects of this system to better treat diabetes: 1) by blocking DPP-IV, the major degrading enzyme of GLP-1, with gliptins 2) the direct administration of long-acting GLP-1 analogues (e.g

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GIP signaling does not have the same provocative effect on the gut