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Hydroquinone has been in use for over 50 years to specifically address facial spots caused by sun damage or freckles, patches (melasma), or dark scars due to injury or disease (like acne or chicken pox)

This mechanism is more aggressive and tends to produce more pronounced swelling, pain, and inflammation

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Reconstituted solutions should be refrigerated (28C) and used within a defined window per laboratory SOPs

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