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In the MitoPark PD mice, in which mitochondrial function is impaired in the dopaminergic neurons, PT320, a sustained release formulation of the GLP-1RA exenatide, reduced ROS production and improved tyrosine hydroxylase expression
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By introducing GLP-1 hormone to our body via injection, we signal to our beta cells to produce insulin and control blood sugar levels
Based on these results, a tailored treatment plan can be developed, including a specific dosage, frequency, and duration for the injections
More recent laboratory investigations have examined DSIP for potential antioxidant properties and cytoprotective effects in cell culture models, exploring whether the peptide influences oxidative stress markers at the cellular level
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The peptide clears quickly, but the biological machinery it activates keeps running
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