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A landmark human trial published in Nature Medicine by Depommier and colleagues (2019) showed that pasteurized Akkermansia supplementation improved insulin sensitivity, reduced total cholesterol, and decreased body weight slightly in overweight and obese individuals over a three-month period
inhibition of this pathway can reduce macrophage activation (Mao et al., 2022)
Epub 2023 Oct 20
If anything looks off or the dates have passed, discard and use a fresh vial
Clinical trial data shows arthralgia incidence is generally similar to placebo, though some musculoskeletal symptoms appear in certain product summaries with varying frequency