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165 In another study, a distinct senescence-like tetraspanin-8 (TSPAN8)+myofibroblastic CAF (myCAF) subgroup potentiates tumor stemness through SASP-associated factors IL-6 and IL-8, thereby promoting chemotherapy resistance in breast cancer
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In 3-KO mice, these reductions were absent, reinforcing the idea that 3-AR plays a necessary role in regulating the response of brown adipose tissue to these agents [2]
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