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Furthermore, based on preclinical evidence suggesting that muscle-derived IL-6 may enhance postprandial GLP-1 secretion [90], it has been proposed that GLP-1RAs could modulate metabolic and inflammatory processes through this pathway [39]
Long-acting glucagon-like peptide-1 (GLP-1) analogues marketed for treatment of type 2 diabetes mellitus have been tested and have shown encouraging protective actions in experimental models of AD and PD as well as in initial clinical trials
Medically reviewed by Dr Spyridon Vlachos, Consultant Plastic Surgeon (GMC: 7522950)
According to the NIDDK, these medications reduce appetite and slow gastric emptying, which increases fullness and decreases hunger the same mechanism that supports weight management goals but also means many users eat significantly less food than before
And for patients, the message is nuanced
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