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Melatonin is an OTC hormone supplement that mainly shifts sleep timing through the circadian system

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As mass-produced drugs became the norm, local pharmacies mostly shifted from making drugs to holding stockpiles of medications, and were tasked with dispensing the correct dosage and giving guidance to patients

10.1038/ncomms11312 104 Keren-ShaulH.SpinradA.WeinerA.Matcovitch-NatanO.Dvir-SzternfeldR.UllandT