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65 reported that astaxanthin, a carotenoid regarded as a highly potent antioxidant, ameliorated parvalbumin-positive neuron deficits and AD-related pathology in the hippocampi of App NL-G-F mice

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The results showed no significant differences in any of the indicators, indicating that FOXO4-DRI treatment did not adversely affect liver or kidney function or cell viability in mice (Supplementary Figures S2AC)