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10.1126/science.aau2818 168 PanY.GanM.WuS.HeY.FengJ.JingY.et al (2024)
It appears in two variants, GLP-1 (7-36)-NH2 and GLP-1 (7-37)
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FIGURE 4 This is complicated because as a polar, charged tripeptide, transport of GSH is significantly inhibited by the blood-brain barrier (BBB), thus limiting effective delivery to brain-resident immune cells such as microglia which are central drivers of neuroinflammatory pathology (Valdovinos-Flores and Gonsebatt, 2012
In its reduced state, it is "active" and ready to neutralize free radicals
This is not an FDA-approved combination
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